The capital's first cross-borough lower traffic neighbourhood has been set up by Newham and Waltham Forest Councils.
The two councils will set up an experimental Low Traffic Neighbourhood (LTN) at their border.
The scheme will aim to reduce traffic, noise and pollution by encouraging walking, cycling and public transport use.
Cllr James Asser, Newham’s cabinet member for environment, highways and sustainable transport, said: 'This experimental scheme is designed to stop drivers using our quiet residential areas as ‘rat-runs’ where vehicles cut through our neighbourhoods to avoid main roads, bringing with them pollution, congestion and road safety hazards.'
Large planters will be used to restrict access for motorised vehicles in some streets, while others will have CCTV and signage installed to create no entry streets. This will be enforced by Automatic Number Plate Recognition cameras, with fines issued for those that fail to comply.
Cllr Clyde Loakes, deputy leader for Waltham Forest Council, said: 'These traffic calming measures make streets more pleasant to use, due to there being less traffic, noise and pollution.'
