Housing and new offices are set to go ahead on a former Toys R Us site in Southampton.
The first phase of the £150m scheme will be put forward when Southampton City Council meets next week.
If approved it will start with 275 residential units in three buildings and a new 70,000 sq ft office building opposite the city's central station.
The council says the scheme will also act as a catalyst for further investment in the Mayflower Quarter, one of the largest urban regeneration areas in the UK.
Council leader Christopher Hammond said: 'Southampton needs world class public realm and to open up more of its waterfront for our residents and visitors to enjoy.
'The Mayflower Quarter gives us a unique opportunity as one of the largest urban regeneration sites in the UK.
‘The old Toys R Us site is the first phase of improving this important gateway into the city.
'We’re excited to bring these transformative plans to full council to enable 275 new homes and an iconic new office building that meets the highest environmental standards.
'The council will be an active partner to help provide an economic boost for the city and to create new skilled jobs for our citizens.'